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DNA IQ™ System

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DNA Isolation System For Use with STR Analysis

  • One simple system for use with casework, paternity and database samples
  • Extract DNA from a variety of sample types, including stains and liquid samples
  • Remove PCR inhibitors and contaminants frequently encountered in casework samples

Size

Catalog number selected: DC6701

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DNA IQ™ System
100 reactions
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Cleaner DNA with a Simple, Rapid System

The DNA IQ™ System is a DNA isolation system designed specifically for forensic and paternity laboratories. This system employs novel paramagnetic particles to prepare clean samples for short tandem repeat (STR) analysis easily and efficiently. The DNA IQ™ System can be used to extract DNA from a variety of sample types, including buccal swabs, liquid blood and stains on FTA® and other blood cards. 

When working with larger sample volumes, such as those found in paternity and databasing, the DNA IQ™ System delivers a consistent amount of total DNA without extra quantitation steps prior to amplification. The DNA IQ™ System is flexible and sensitive to minute sample sizes. In addition, no harmful organic solvents such as phenol and chloroform are used, so use of a hood is not required and disposal of hazardous chemicals is eliminated.

The DNA IQ™ System has been tested with the PowerQuant® and Plexor® HY Systems and PowerPlex® Systems to ensure a streamlined process. This translates into reliable products that give optimal results from isolation to quantitation and STR analysis.

ForensicGrade

Promega forensic products are manufactured in alignment with the ISO 18385 standard. This standard ensures minimal risk of human DNA contamination for products used to collect, store and analyze biological materials for forensic purposes. Learn more.

Process Difficult Samples

The unique DNA IQ™ Resin eliminates PCR inhibitors and contaminants frequently encountered in casework (e.g., denim, leather and soil). Even bloodstains as small as 0.1µl can be processed and the DNA amplified to give a complete STR profile. To extract stains, just heat your sample in Lysis Buffer for 30 minutes and centrifuge. Add DNA IQ™ Resin, and wash your sample using a magnetic stand. Thirty minutes later, you have purified DNA.

Some samples, such as tissue and hair, require pretreatment with Proteinase K. In addition, extracting DNA can be difficult from substrates such as denim, envelopes, carpet, etc.

The Tissue and Hair Extraction Kit increases DNA yield from challenging casework samples and substrates. The kit uses Proteinase K and other reagents to remove proteins and other components from the DNA, helping to ensure maximal yield and recovery of DNA from casework samples. The DNA then can be purified using the DNA IQ™ System.

Available Separately

Required Products* Size Cat.#
DNA IQ™ Spin Baskets 50/pack V1225
ClickFit Microtube, 1.5ml (recommended) 100/pack V4745
MagneSphere® Technology Magnetic Separation Stand Two-position, 1.5ml Z5332
Twelve-position, 1.5ml Z5342

 *Required for manual protocol.

Stand-Alone Products Size Cat.#
Lysis Buffer 150ml A8261
2X Wash Buffer 70ml A8271
Elution Buffer 50ml A8281
DNA IQ™ Resin 50ml A8251
8ml A8258
Proteinase K 100mg V3021
DTT, Molecular Grade (Dry Powder) 5g V3151
25g V3155

Want to Automate?

Save time by automating the DNA IQ™ System on the Biomek® 4000 (Beckman Coulter), Freedom EVO (Tecan), or MicroLab STAR (Hamilton) liquid handlers. Follow up with DNA quantification, and import the quantitation data into the STR Normalization Manager Software to automate your PCR amplification setup.

Automate your DNA Extraction

Component volumes in the DNA IQ™ System (Cat.# DC6700 and DC6701) may not be sufficient for automating the process on large platforms. However, the components are available for purchase as stand-alone products. Please contact your local representative to discuss required quantities for your platform and workflow and to schedule the required installation and training services.

Specifications

You are viewing: DC6701 Change Configuration

What's in the box?

Item Part # Size Available Separately

Resin

A825F 1 × 900μl View Product

Lysis Buffer

A826F 1 × 40ml View Product

2X Wash Buffer

A827F 1 × 30ml View Product

Elution Buffer

A828G 1 × 15ml View Product

Certificate of Analysis

Search by lot number

Use Restrictions

For Research Use Only. Not for Use in Diagnostic Procedures.

Storage Conditions

DD

Specifications

You are viewing: DC6700 Change Configuration

What's in the box?

Item Part # Size Available Separately

Resin

A825B 1 × 3ml View Product

Lysis Buffer

A826B 1 × 150ml View Product

2X Wash Buffer

A827B 1 × 70ml View Product

Elution Buffer

A828B 1 × 50ml View Product

Certificate of Analysis

Search by lot number

Use Restrictions

For Research Use Only. Not for Use in Diagnostic Procedures.

Storage Conditions

DD

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